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The Risks Of Modafinil Abuse

Significant accumulation of modafinil sulfone has been noticed after a quantity of doses as a end result of its long elimination half-life of 40 hours. Auto-induction of metabolizing enzymes, most importantly cytochrome P-450 CYP3A4, has additionally been observed in vitro after incubation of main cultures of human hepatocytes with modafinil and in vivo after prolonged […]

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